Isolation of insect anti-feeding principles in Orixa japonica thunb.

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Rat small intestine muscle relaxation alkaloids from Orixa japonica leaves.

Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.

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ژورنال

عنوان ژورنال: Agricultural and Biological Chemistry

سال: 1977

ISSN: 0002-1369,1881-1280

DOI: 10.1271/bbb1961.41.1263